Findings

What do systematic reviews say?

5 questions · 5 findings · 4 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

PCC vs FVIIa

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

It is very uncertain whether PCC changes mortality (30‐day) compared with FVIIa (very low certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 1.07 [0.38, 3.03]
3 studies · 278 participants
Very low

PCC vs usual care

Mortality (30‐day) · cardiac surgery for the treatment of non‐surgical bleeding

PCC showed no clear difference in mortality (30‐day) compared with standard treatment (moderate certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 0.53 [0.12, 2.35]
2 studies · 149 participants
Moderate

Perioperative alcohol cessation intervention vs treatment

In‐hospital and 30‐day mortality · adult surgical patients consuming 3 or more units of alcohol per day

Perioperative alcohol cessation intervention showed no clear difference in in‐hospital and 30‐day mortality compared with treatment (low certainty).

1 finding from 1 review

Perioperative alcohol cessation intervention for postoperative complications 2018 · Cochrane Headline outcomes only
RR 0.47 [0.07, 2.96]
3 studies · 122 participants
Low

Totally percutaneous vs cut‐down femoral artery access

Short‐term mortality (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with cut‐down femoral artery access (low certainty).

1 finding from 1 review

Totally percutaneous versus surgical cut‐down femoral artery access for elective bifurcated abdominal endovascular… 2023 · Cochrane Headline outcomes only
RR 1.5 [0.06, 36.18]
2 studies · 181 participants
Low

Buffered vs non‐buffered crystalloid intravenous fluid

Mortality (in‐hospital death and 30‐day mortality) · adults receiving intravenous fluids whilst undergoing any form of surgery

Buffered showed no clear difference in mortality (in‐hospital death and 30‐day mortality) compared with non‐buffered crystalloid intravenous fluid (low certainty).

1 finding from 1 review

Perioperative administration of buffered versus non‐buffered crystalloid intravenous fluid to improve outcomes… 2017 · Cochrane Headline outcomes only
OR 1.85 [0.37, 9.33]
3 studies · 267 participants
Low