Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 10 findings · 5 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 10%Low 3 · 30%Moderate 3 · 30%High 3 · 30%

Oxygenation vs no oxygenation during the apnoeic period preceding intubation

All‐cause mortality · people requiring tracheal intubation

Oxygenation showed no clear difference in mortality compared with no oxygenation during the apnoeic period preceding intubation (low certainty).

1 finding from 1 review

Active cerebral oxygenation monitoring vs blinded cerebral oxygenation monitoring

Intraoperative mortality or postoperative mortality: Death ( · children and adults undergoing surgery

Active cerebral oxygenation monitoring showed no clear difference in intraoperative mortality or postoperative mortality: Death ( compared with blinded cerebral oxygenation monitoring (low certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality at 6 months (subgroup) · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: ECPR subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: all ECMO studies · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: all ECMO studies compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VV ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) probably leads to lower all‐cause mortality: VV ECMO subgroup compared with conventional care (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) vs usual care

All‐cause mortality: VA ECMO subgroup · severe cardiorespiratory failure and cardiac arrest

Summary of findings table ‐ Extracorporeal membrane oxygenation (ECMO) showed no clear difference in all‐cause mortality: VA ECMO subgroup compared with conventional care (low certainty).

1 finding from 1 review

Higher vs lower FiO2 or targets of arterial oxygenation

All‐cause mortality: range 1 mo to 1 y · adults admitted to the ICU

It is very uncertain whether higher changes all‐cause mortality: range 1 mo to 1 y compared with lower FiO2 or targets of arterial oxygenation (very low certainty).

1 finding from 1 review