Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

108 questions · 108 findings · 38 reviews · Hepato-Biliary

No studies found 13 · 12%GRADE not reported 4 · 3.7%Very low 80 · 74.1%Low 8 · 7.4%Moderate 3 · 2.8%High 0 · 0%

Intervention vs control

60‐day mortality ‐ Recombinant factor VIIa (rFVIIa) versus control · Patients with liver transplantation.

It is very uncertain whether intervention changes 60‐day mortality ‐ Recombinant factor VIIa (rFVIIa) versus control compared with control (very low certainty).

1 finding from 1 review

Intervention vs any comparison

Mortality ‐ Topical povidone iodine gel versus no topical povidone iodine gel · patients undergoing liver resections

It is very uncertain whether intervention changes mortality ‐ Topical povidone iodine gel versus no topical povidone… compared with comparison (very low certainty).

1 finding from 1 review

Exercise vs control

All‐cause mortality at end of intervention (range 2–10 months) · adult patients after liver transplantation.

It is very uncertain whether exercise changes all‐cause mortality at end of intervention (range 2–10 months) compared with control (very low certainty).

1 finding from 1 review

Non‐absorbable disaccharides vs placebo or no intervention

All‐cause mortality · prevention and treatment of hepatic encephalopathy in people with cirrhosis

Non‐absorbable disaccharides probably leads to lower mortality compared with placebo/no intervention (moderate certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

All‐cause mortality · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes all‐cause mortality compared with sham or no intervention (very low certainty).

1 finding from 1 review