Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

17 questions · 19 findings · 6 reviews · Gynaecology and Fertility

No studies found 1 · 5.3%GRADE not reported 0 · 0%Very low 8 · 42.1%Low 10 · 52.6%Moderate 0 · 0%High 0 · 0%

Metformin vs placebo or no treatment

Miscarriage · women with polycystic ovary syndrome

Metformin showed no clear difference in miscarriage rate per woman compared with placebo or no treatment (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Metformin combined with clomiphene citrate vs clomiphene

Miscarriage · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate showed no clear difference in miscarriage rate per woman compared with clomiphene citrate alone (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Long‐term GnRH agonist therapy vs no additional therapy

Miscarriage · patients with endometriosis prior to standard IVF/ICSI

It is very uncertain whether long‐term GnRH agonist therapy changes miscarriage rate compared with no additional therapy (very low certainty).

1 finding from 1 review

Starting administration of the progestogen earlier vs starting administration of the progestogen later

Miscarriage · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

It is very uncertain whether starting administration of the progestogen earlier changes miscarriage Rate compared with starting administration of the progestogen later (very low certainty).

1 finding from 1 review