Findings

What do systematic reviews say?

3 questions · 5 findings · 3 reviews · Heart

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 0 · 0%Moderate 2 · 40%High 2 · 40%

Interrupted vs uninterrupted anticoagulation therapy

Minor bleeding · adults with arrhythmias undergoing catheter ablation

It is very uncertain whether interrupted changes minor bleeding compared with uninterrupted anticoagulation therapy (very low certainty).

1 finding from 1 review

Interrupted versus uninterrupted anticoagulation therapy for catheter ablation in adults with arrhythmias 2021 · Cochrane Headline outcomes only
RR 1.01 [0.46, 2.22]
9 studies · 3843 participants
Very low

clopidogrel plus aspirin vs aspirin

Minor bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin probably leads to higher minor bleeding compared with aspirin alone (moderate certainty).

1 finding from 1 review

Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events 2017 · Cochrane Headline outcomes only
RR 2.03 [1.75, 2.36]
8 studies · 14731 participants
Moderate

Factor Xa inhibitors vs Anticoagulants

Minor bleeding · Anticoagulants in ACS

Factor Xa inhibitors showed no clear difference in minor bleeding at 30 days compared with anticoagulants (high certainty).

3 findings from 1 review

Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.7 [0.14, 3.39]
2 studies · 20404 participants
High
Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 1.76 [0.52, 5.94]
1 study · 326 participants
Moderate
Factor Xa inhibitors for acute coronary syndromes 2011 · Cochrane Headline outcomes only
RR 0.34 [0.28, 0.43]
1 study · 20078 participants
High