Findings

What do systematic reviews say?

6 questions · 6 findings · 4 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 16.7%Low 3 · 50%Moderate 2 · 33.3%High 0 · 0%

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) vs broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all outcomes

Endometritis · women undergoing caesarean section

Antistaphylococcal cephalosporins C1 and C2 (1st and 2nd generation) showed no clear difference in maternal endometritis compared with broad spectrum penicillins plus betalactamase inhibitors P2+ ‐ all… (low certainty).

1 finding from 1 review

Different classes of antibiotics given to women routinely for preventing infection at caesarean section 2021 · Cochrane Headline outcomes only
RR 1.1 [0.76, 1.6]
7 studies · 1161 participants
Low

Antibiotics vs no antibiotics

Endometritis · women undergoing caesarean section

Antibiotics probably leads to lower maternal endometritis compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section 2014 · Cochrane Headline outcomes only
RR 0.38 [0.34, 0.42]
83 studies · 13548 participants
Moderate

Antibiotics vs no antibiotics

Endometritis · Women undergoing elective cesarean section

Antibiotics probably leads to lower maternal endometritis compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section 2014 · Cochrane Headline outcomes only
RR 0.38 [0.24, 0.61]
15 studies · 2502 participants
Moderate

Planned early birth vs expectant management

Maternal infectious morbidity (chorioamnionitis and/or endometritis) · women with prelabour rupture of membranes at term (37 weeks' gestation or later)

Planned early birth may leads to lower maternal infectious morbidity (chorioamnionitis and/or endometritis) compared with expectant management (low certainty).

1 finding from 1 review

Planned early birth versus expectant management (waiting) for prelabour rupture of membranes at term (37 weeks or more) 2017 · Cochrane Headline outcomes only
RR 0.49 [0.33, 0.72]
8 studies · 6864 participants
Low

Antibiotics vs placebo or no antibiotic

Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Late induction of labour · pregnant women with prelabour rupture of membranes at or near term

It is very uncertain whether any antibiotic changes maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (very low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 0.34 [0.08, 1.47]
2 studies · 838 participants
Very low

Antibiotics vs placebo or no antibiotic

Maternal infectious morbidity (chorioamnionitis and/or endometritis) ‐ Early induction of labour · pregnant women with prelabour rupture of membranes at or near term

Any antibiotic showed no clear difference in maternal infectious morbidity (chorioamnionitis and/or endometritis)… compared with placebo or no antibiotic (subgrouped by timing of induction of labour) (low certainty).

1 finding from 1 review

Antibiotics for prelabour rupture of membranes at or near term 2014 · Cochrane Headline outcomes only
RR 1.15 [0.64, 2.08]
1 study · 1640 participants
Low