Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 19 findings · 7 reviews

No studies found 5 · 26.3%GRADE not reported 0 · 0%Very low 5 · 26.3%Low 4 · 21.1%Moderate 1 · 5.3%High 4 · 21.1%

Recombinant follicle stimulating hormone vs urinary‐derived gonadotrophins

Live birth rate per woman · ovulation induction in polycystic ovarian syndrome

Recombinant follicle stimulating hormone showed no clear difference in live birth rate per woman compared with urinary‐derived gonadotrophins (low certainty).

1 finding from 1 review

rFSH vs urinary‐derived gonadotrophins

Ongoing pregnancy / live birth rate per woman · patients with ovarian stimulation in assisted reproductive technology cycles

rFSH showed no clear difference in live birth (or ongoing pregnancy) by urinary gonadotrophin compared with urinary gonadotrophins: primary analyses (high certainty).

4 findings from 1 review
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Human menopausal gonadotrophin or highly purified human menopausal gonadotrophin vs urinary follicle stimulating hormone

Live birth rate per woman · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes live birth rate per woman compared with urinary follicle stimulating hormone (very low certainty).

1 finding from 1 review

Metformin combined with clomiphene citrate vs clomiphene

Live birth rate per woman · women with polycystic ovary syndrome

Metformin combined with clomiphene citrate showed no clear difference in live birth rate per woman compared with clomiphene citrate alone (low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews

Metformin vs clomiphene

Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome

It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).

1 finding from 1 review · compare the 2 reviews