Cochrane · systematic review · CD005071

Gonadotrophins for idiopathic male factor subfertility

Attia, AM, Abou‐Setta, AM, Al‐Inany, HG · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
2
current version
GRADE rated
2
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 50%Low 0 · 0%Moderate 1 · 50%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Gonadotrophins versus placebo/no treatment for the treatment of idiopathic male subfertility for idiopathic male factor subfertility

Population: Men with idiopathic male factor subfertility
2 questions
OutcomeEffectEvidenceStatus / GRADE
Live birth rate per couple randomly assigned
Gonadotrophins vs placebo/no treatment
OR 9.31 [1.17, 73.75]1 study · 30 participantsVery low
Downgraded: risk of bias, inconsistency
Spontaneous pregnancy rate per couple randomly assigned
Gonadotrophins vs placebo/no treatment
OR 4.94 [2.13, 11.44]5 studies · 412 participantsModerate
Downgraded: risk of bias