Question · asked by 1 review

Gonadotrophins vs placebo/no treatment: Live birth rate per couple

It is very uncertain whether gonadotrophins changes live birth rate per couple randomly assigned compared with placebo/no treatment (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Gonadotrophins vs placebo/no treatment
Live birth rate per couple randomly assigned · Men with idiopathic male factor subfertility
It is very uncertain whether gonadotrophins changes live birth rate per couple randomly assigned compared with placebo/no treatment (very low certainty).
Gonadotrophins for idiopathic male factor subfertility (2013) · Cochrane Headline outcomes only
OR 9.31 [1.17, 73.75]1 study · 30 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Gonadotrophins for idiopathic male factor subfertility
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.