Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 4 reviews · Schizophrenia

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 80%Low 0 · 0%Moderate 0 · 0%High 1 · 20%

Maintenance treatment with antipsychotic drugs vs placebo/no treatment

Acceptability of treatment ‐ leaving the study early · schizophrenia

Maintenance treatment with antipsychotic drugs leads to lower leaving the study early: due to any reason (acceptability of… compared with placebo/no treatment (high certainty).

1 finding from 1 review

Adjunctive carbamazepine + antipsychotics vs placebo/no adjunctive treatment + antipsychotics

Leaving the study early · patients with schizophrenia

It is very uncertain whether adjunctive carbamazepine + antipsychotics changes acceptability of treatment Leaving the study early due to any reason compared with placebo/no adjunctive treatment + antipsychotics (very low certainty).

1 finding from 1 review

Perazine vs placebo

Leaving the study early · patients with schizophrenia

It is very uncertain whether perazine changes acceptability of treatment Leaving the study early due to any reason compared with placebo (very low certainty).

1 finding from 1 review

ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS vs placebo/no adjunctive treatment + antipsychotics

Unacceptability of treatment (drop-outs / leaving study early) · patients with schizophrenia

It is very uncertain whether ADJUNCTIVE BENZODIAZEPINES + ANTIPSYCHOTICS changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO/NO ADJUNCTIVE TREATMENT + ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

BENZODIAZEPINES AS SOLE TREATMENT vs placebo

Unacceptability of treatment (drop-outs / leaving study early) · patients with schizophrenia

It is very uncertain whether BENZODIAZEPINES AS SOLE TREATMENT changes leaving the study early due to any reason (overall acceptability of… compared with PLACEBO (very low certainty).

1 finding from 1 review