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What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 4 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 1 · 20%High 2 · 40%

Heparin plus aspirin vs aspirin

Intrauterine growth restriction · women with persistent antiphospholipid antibodies and recurrent pregnancy loss

It is very uncertain whether heparin plus aspirin changes intrauterine growth restriction compared with aspirin (very low certainty).

1 finding from 1 review

Intervention not reported

Intrauterine growth restriction · All pregnant women receiving either vitamin C supplementation or control either in areas where there is inadequate dietary intake or where…

The intervention showed no clear difference in intrauterine growth restriction (high certainty).

1 finding from 1 review

Vitamin E vs placebo, no placebo or other supplements

Intrauterine growth restriction · pregnant women receiving vitamin E supplementation or control, living in areas where there is either inadequate dietary intake of vitamin…

Any vitamin E supplementation showed no clear difference in intrauterine growth restriction (various definitions) compared with placebo, no placebo or other supplements (high certainty).

1 finding from 1 review