Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Metformin vs glibenclamide ‐ maternal outcomes

Induction of labour · women with gestational diabetes mellitus

Metformin showed no clear difference in induction of labour compared with glibenclamide ‐ maternal outcomes (low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 0.81 [0.61, 1.07]
1 study · 159 participants
Low

Metformin vs insulin

Induction of labour · women with type 2 diabetes

It is very uncertain whether maternal outcomes: oral anti‐diabetic agent (metformin) changes induction of labour compared with insulin (very low certainty).

1 finding from 1 review

Oral anti‐diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational… 2017 · Cochrane Headline outcomes only
RR 1.42 [0.62, 3.28]
2 studies · 35 participants
Very low