Findings

What do systematic reviews say?

8 questions · 8 findings · 7 reviews · Emergency and Critical Care

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No studies found 1 · 12.5%GRADE not reported 0 · 0%Very low 2 · 25%Low 0 · 0%Moderate 3 · 37.5%High 2 · 25%

Protocol‐directed sedation management vs usual care

Length of hospital stay · mechanically ventilated ICU adults and children requiring sedation management

1 finding from 1 review

Protocol‐directed sedation versus non‐protocol‐directed sedation in mechanically ventilated intensive care adults and… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 2927 participants
Moderate

Etomidate vs all other induction agents

Length of hospital stay · patients with endotracheal intubation in critically ill patients

1 finding from 1 review

Single induction dose of etomidate versus other induction agents for endotracheal intubation in critically ill patients 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 152 participants
Moderate

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

Length of hospital stay · Critically ill adults receiving mechanical ventilation in ICU

Daily sedation interruption showed no clear difference in hospital length of stay (days) compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

1 finding from 1 review

Daily sedation interruption versus no daily sedation interruption for critically ill adult patients requiring invasive… 2014 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1232 participants
Moderate

Intervention not reported

Hospital length of stay (days) · critically ill adults and children requiring weaning from mechanical ventilation

The intervention showed no clear difference in hospital length of stay (days) (high certainty).

1 finding from 1 review

Automated versus non‐automated weaning for reducing the duration of mechanical ventilation for critically ill adults… 2014 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 749 participants
High

Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN

Length of hospital stay · critically ill adult patients

The review found no eligible studies for this question.

1 finding from 1 review

Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Early enteral nutrition vs delayed enteral nutrition

Length of hospital stay · critically ill adult patients

1 finding from 1 review

Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Corticosteroids vs placebo or usual care

Duration of hospital stay MCID: 1 day absolute difference · children and adults with sepsis

1 finding from 1 review

Corticosteroids for treating sepsis in children and adults 2019 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 8795 participants
High

Hypocaloric nutrition vs control

Length of hospital stay · critically ill adult patients

1 finding from 1 review

Prescribed hypocaloric nutrition support for critically‐ill adults 2018 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1677 participants
Very low