Findings

What do systematic reviews say?

17 questions · 18 findings · 6 reviews · ENT

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No studies found 3 · 16.7%GRADE not reported 0 · 0%Very low 13 · 72.2%Low 2 · 11.1%Moderate 0 · 0%High 0 · 0%

Antibiotics vs no treatment or placebo on top of topical antibiotics

Hearing · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics with steroids vs topical antibiotics

Hearing · people (of any age) with chronic suppurative otitis media or ear discharge

2 findings from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 135 participants
Very low
Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 419 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 38 participants
Very low

Topical antibiotics vs placebo/no treatment

Hearing · patients with mucopurulent otorrhoea

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Very low

Topical antibiotics vs acetic acid

Hearing · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 107 participants
Very low

Antibiotics vs no treatment/placebo

Hearing · children with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Antibiotics vs no treatment

Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)

1 finding from 1 review

Antibiotics for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether antibiotics changes hearing ‐ return to normal hearing (as complete improvement in… compared with placebo (very low certainty).

1 finding from 1 review

Antibiotics for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes only
Peto OR 9.59 [3.51, 26.18]
Studies not reported
Very low

Topical quinolone vs povidone‐iodine

Hearing · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Topical antibiotics with steroids vs placebo/no treatment

Hearing · chronic suppurative otitis media

1 finding from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 123 participants
Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

Hearing · schoolchildren with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 204 participants
Very low

Topical quinolone vs boric acid

Average change in hearing from baseline · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 390 participants
Low

Topical quinolone vs intramuscular gentamicin

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

Hearing · adults with CSOM

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 56 participants
Very low

Topical quinolone vs quinolones

Hearing · people (of any age) with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Hearing · CSOM, recurrence of CSOM or suppuration following mastoidectomy or tympanoplasty

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Quinolone vs aminoglycosides

Hearing · people (of any age) with CSOM

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 132 participants
Very low