What do systematic reviews say?

Pulmonary rehabilitation plus inspiratory muscle training vs pulmonary rehabilitation alone

• Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 908 participants
  Low
• Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 657 participants
  Very low

Pulmonary rehabilitation vs usual care

• Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease 2016 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1003 participants
  High

Oral factor Xa inhibitors vs conventional anticoagulation

The review found no eligible studies for this question.

• Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oral direct thrombin inhibitors (DTIs) vs conventional anticoagulation

The review found no eligible studies for this question.

• Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Inspiratory muscle training vs control or sham

• Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 182 participants
  Very low
• Inspiratory muscle training, with or without concomitant pulmonary rehabilitation, for chronic obstructive pulmonary… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 86 participants
  Moderate

Integrated disease management interventions vs usual care

• Integrated disease management interventions for patients with chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  18 studies · 4321 participants
  Moderate

Self‐management interventions vs usual care

• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1582 participants
  High

Intervention not reported

• Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 212 participants
  Moderate

Vitamin D vs placebo or no intervention

The review found no eligible studies for this question.

• Vitamin D supplementation for prevention of cancer in adults 2014 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 267 participants
  Low

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

• Non‐invasive ventilation during exercise training for people with chronic obstructive pulmonary disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 48 participants
  Moderate

NMES and exercise vs exercise (with or without sham NMES)

• Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 122 participants
  Very low

NMES vs usual care with or without sham interventions

• Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 72 participants
  Very low

Summary of findings table ‐ Systemic therapy vs control

• Systemic therapies for preventing or treating aromatase inhibitor‐induced musculoskeletal symptoms in early breast… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 208 participants
  Very low

Smart technology vs face‐to‐face/digital and/or written support

• Computer and mobile technology interventions for self‐management in chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 472 participants
  Low

Summary of findings table ‐ Cannabis vs placebo

• Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1942 participants
  Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 219 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 164 participants
  Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 259 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 200 participants
  Very low

Yoga vs no breathing exercises

• Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 45 participants
  Moderate

Diaphragmatic breathing vs no breathing exercises

• Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Moderate