Findings

What do systematic reviews say?

34 questions · 34 findings · 14 reviews

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No studies found 8 · 23.5%GRADE not reported 4 · 11.8%Very low 10 · 29.4%Low 7 · 20.6%Moderate 2 · 5.9%High 3 · 8.8%

Exercise vs no exercise or placebo exercise

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 656 participants
Very low

Intravenous magnesium sulphate vs placebo

HRQoL score (Child‐reported PedsQL generic scale) at 1 week · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 202 participants
Low

Aerobic exercise vs no exercise or placebo exercise

Quality of Life: SF‐36 (physical component) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 306 participants
Very low

Resistance training vs no exercise or placebo exercise

Quality of Life: SF‐36 (physical component) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 176 participants
Very low

Aerobic exercise and strength training vs no exercise or placebo exercise

Quality of Life: SF‐36 (physical component) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 228 participants
Very low

Exercise vs no exercise or placebo exercise

Quality of Life: SF‐36 (physical component) · adults undergoing maintenance dialysis

1 finding from 1 review

Exercise training for adults undergoing maintenance dialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 656 participants
Low

Spironolactone 100 mg vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Finasteride 5 mg to 7.5 mg vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Metformin 500 mg to 2550 mg per day vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Flutamide 250 mg b.i.d. vs placebo

Change in health‐related quality of life (HRQOL) ‐ not measured · women with hirsutism

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intravenous magnesium sulphate vs placebo

HRQoL score (Child‐reported PedsQL sickle cell disease module) at 1 week · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 202 participants
Low

Intravenous magnesium sulphate vs placebo

HRQoL score (Child‐reported PedsQL multidimensional fatigue scale) at 1 week · people with sickle cell disease

1 finding from 1 review

Magnesium for treating sickle cell disease 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 202 participants
Low

Belimumab 10 mg/kg vs placebo

Change in HRQOL, on SF‐36 PCS score at 52 weeks Improvement in SF‐36 PCS score from baseline ( · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)

Belimumab 10 mg/kg probably leads to higher change in HRQOL, on SF‐36 PCS score at 52 weeks Improvement in SF‐36… compared with placebo (moderate certainty).

1 finding from 1 review

Belimumab for systemic lupus erythematosus 2021 · Cochrane Headline outcomes only
MD 1.6 [0.3, 2.9]
2 studies · 801 participants
Moderate

Antibiotics vs placebo

HRQoL: total score · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The 2 larger studies (Albert 2011; Sethi…

1 finding from 1 review

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2237 participants
High