Findings

What do systematic reviews say?

7 questions · 7 findings · 6 reviews · Pregnancy and Childbirth

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 3 · 42.9%High 0 · 0%

Endometritis · Women who had normal vaginal births

It is very uncertain whether routine antibiotic prophylaxis changes endometritis compared with no treatment or placebo (very low certainty).

1 finding from 1 review

Routine antibiotic prophylaxis after normal vaginal birth for reducing maternal infectious morbidity 2017 · Cochrane Headline outcomes only
RR 0.28 [0.09, 0.83]
2 studies · 1364 participants
Very low

Incidence of puerperal infection (endometritis) · women with episiotomy repair following vaginal birth

1 finding from 1 review

Antibiotic prophylaxis for episiotomy repair following vaginal birth 2017 · Cochrane Headline outcomes only
no estimate extracted
73 participants
Very low

Endometritis · women undergoing caesarean section

Antibiotics probably leads to lower maternal endometritis compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section 2014 · Cochrane Headline outcomes only
RR 0.38 [0.34, 0.42]
83 studies · 13548 participants
Moderate

Endometritis · Women undergoing elective cesarean section

Antibiotics probably leads to lower maternal endometritis compared with no antibiotics (moderate certainty).

1 finding from 1 review

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section 2014 · Cochrane Headline outcomes only
RR 0.38 [0.24, 0.61]
15 studies · 2502 participants
Moderate

Endometritis · Women undergoing operative vaginal delivery

Any antibiotics showed no clear difference in endometritis № of participants: 3813 (2 RCTs) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Antibiotic prophylaxis for operative vaginal delivery 2020 · Cochrane Headline outcomes only
RR 0.32 [0.04, 2.64]
Studies not reported
Low

Puerperal sepsis/postpartum endometritis · women in the second or third trimester of pregnancy before labour and delivery

Prophylactic antibiotics probably leads to lower puerperal sepsis/postpartum endometritis compared with placebo (moderate certainty).

1 finding from 1 review

Endometritis · pregnant women undergoing caesarean section

Intravenous route showed no clear difference in endometritis compared with irrigation (lavage) (low certainty).

1 finding from 1 review