Findings

What do systematic reviews say?

9 questions · 11 findings · 8 reviews · Neonatal

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No studies found 3 · 27.3%GRADE not reported 1 · 9.1%Very low 4 · 36.4%Low 2 · 18.2%Moderate 1 · 9.1%High 0 · 0%

High‐dose vs standard‐dose strategies

Length of hospital stay · preterm infants with or at risk for apnea of prematurity

The review found no eligible studies for this question.

3 findings from 1 review

Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
GRADE not reported

Antibiotics vs no antibiotics

Length of hospital stay · symptomatic neonates born through meconium‐stained amniotic fluid

1 finding from 1 review

Antibiotics for neonates born through meconium‐stained amniotic fluid 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Moderate

High‐dose vs standard‐dose strategies

Length of hospital stay · preterm infants at risk for apnea

1 finding from 1 review

Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1 participants
Very low

Intervention not reported

Duration of hospital stay (days) · preterm infants less than 30 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Salbutamol vs placebo/no treatment

Length of hospital stay · patients with the management of transient tachypnea of the newborn

1 finding from 1 review

Salbutamol for transient tachypnea of the newborn 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 338 participants
Low

Short feeding interval vs long feeding interval

Length of hospital stay · preterm infants less than 1500 grams

1 finding from 1 review

Short versus long feeding interval for bolus feedings in very preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 207 participants
Very low

Protein supplementation vs control

Length of hospital stay · preterm infants

1 finding from 1 review

Protein supplementation of human milk for promoting growth in preterm infants 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Very low

Inhaled corticosteroids vs no treatment or placebo

Length of hospital stay · patients with the management of transient tachypnea of the newborn

1 finding from 1 review

Postnatal corticosteroids for transient tachypnoea of the newborn 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Very low

Caffeine vs other methylxanthines

Length of hospital stay · preterm infants

1 finding from 1 review

Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low