Findings

What do systematic reviews say?

5 questions · 5 findings · 3 reviews · Injuries

No studies found 0 · 0%GRADE not reported 2 · 40%Very low 1 · 20%Low 0 · 0%Moderate 2 · 40%High 0 · 0%

Death ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…

The intervention showed no clear difference in death ( (moderate certainty).

1 finding from 1 review

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia 2012 · Cochrane Headline outcomes only
RR 1.04 [0.55, 1.97]
15 studies · 1219 participants
Moderate

Death ( · any patients with conditions outside the marketing license for the intervention, particularly those at risk of bleeding or those whose…

The intervention showed no clear difference in death ( (moderate certainty).

1 finding from 1 review

Recombinant factor VIIa for the prevention and treatment of bleeding in patients without haemophilia 2012 · Cochrane Headline outcomes only
RR 0.91 [0.78, 1.06]
13 studies · 2856 participants
Moderate

Death ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydramine led to lower death ‐ not reported compared with placebo; GRADE not reported.

1 finding from 1 review

Death ‐ not reported · patients with requirement of prophylaxis to avoid allergic and febrile non‐haemolytic transfusion reactions

Acetaminophen plus Diphenhydrammine led to lower death ‐ not reported compared with placebo (Unit of randomisation: transfusion); GRADE not reported.

1 finding from 1 review

Death from all causes during the · adults with traumatic brain injury

It is very uncertain whether the intervention changes death from all causes during the (very low certainty).

1 finding from 1 review