Findings

What do systematic reviews say?

13 questions · 13 findings · 4 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 5 · 38.5%Very low 2 · 15.4%Low 5 · 38.5%Moderate 1 · 7.7%High 0 · 0%

Combination of interventions vs no intervention

Pregnancy‐related deaths · pregnant women

Combination of interventions showed no clear difference in pregnancy‐related deaths compared with no intervention (moderate certainty).

1 finding from 1 review

Health system and community level interventions for improving antenatal care coverage and health outcomes 2015 · Cochrane Headline outcomes only
OR 0.7 [0.39, 1.26]
3 studies · 13756 participants
Moderate

One intervention vs no intervention

Pregnancy‐related deaths · pregnant women

One intervention showed no clear difference in pregnancy‐related deaths compared with no intervention (low certainty).

1 finding from 1 review

Health system and community level interventions for improving antenatal care coverage and health outcomes 2015 · Cochrane Headline outcomes only
OR 0.69 [0.45, 1.08]
10 studies · 114930 participants
Low

Acupuncture vs placebo

Perinatal mortality · Pregnant women with hyperemesis gravidarum

Acupuncture showed no clear difference in stillbirth and neonatal death compared with placebo (low certainty).

1 finding from 1 review

Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
RR 0.57 [0.04, 8.3]
1 study · 36 participants
Low

Corticosteroids vs promethazine

Perinatal mortality · Pregnant women with hyperemesis gravidarum

Corticosteroids showed no clear difference in stillbirth and neonatal death compared with promethazine (low certainty).

1 finding from 1 review

Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
RR 3 [0.13, 69.52]
1 study · 40 participants
Low

Corticosteroids vs placebo

Perinatal mortality · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes stillbirth and neonatal death compared with placebo (very low certainty).

1 finding from 1 review

Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
RR 0.7 [0.15, 3.34]
2 studies · 134 participants
Very low

Intracervical PGE₂ vs placebo

Neonatal death or serious neonatal perinatal morbidity · women requiring induction of labour

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intracervical PGE₂ vs placebo

Serious maternal morbidity or death · women requiring induction of labour

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vaginal misoprostol vs placebo

Neonatal death or serious neonatal perinatal morbidity · women requiring induction of labour

Vaginal misoprostol showed no clear difference in serious neonatal morbidity or death compared with placebo (low certainty).

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
RR 0.34 [0.01, 8.14]
1 study · 77 participants
Low

Vaginal misoprostol vs placebo

Serious maternal morbidity or death · women requiring induction of labour

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vaginal PGE₂ vs placebo or expectant management

Neonatal death or serious neonatal perinatal morbidity · patients with induction of labour at term

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Vaginal PGE₂ vs placebo or expectant management

Serious maternal morbidity or death · patients with induction of labour at term

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Lifestyle vs control ‐ Neonatal and later outcomes

Perinatal (fetal and neonatal death) and later infant mortality · women with gestational diabetes mellitus

Lifestyle showed no clear difference in perinatal (fetal and neonatal death) and later infant mortality compared with control ‐ Neonatal and later outcomes (low certainty).

1 finding from 1 review

Lifestyle interventions for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 0.09 [0.01, 1.7]
2 studies · 1988 participants
Low

Lifestyle vs control ‐ Neonatal and later outcomes

Composite outcome in infant (death, shoulder dystocia, nerve palsy, bone fracture) · women with gestational diabetes mellitus

It is very uncertain whether lifestyle changes composite outcome in infant (death, shoulder dystocia, nerve palsy,… compared with control ‐ Neonatal and later outcomes (very low certainty).

1 finding from 1 review

Lifestyle interventions for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 0.57 [0.21, 1.55]
2 studies · 1930 participants
Very low