Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

222 questions · 224 findings · 82 reviews

No studies found 49 · 21.9%GRADE not reported 16 · 7.1%Very low 57 · 25.4%Low 57 · 25.4%Moderate 36 · 16.1%High 9 · 4%

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Adverse event: Death · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in adverse event: Death compared with standard care (low certainty).

1 finding from 1 review