Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

65 questions · 66 findings · 16 reviews · Gut

No studies found 24 · 36.4%GRADE not reported 0 · 0%Very low 15 · 22.7%Low 13 · 19.7%Moderate 6 · 9.1%High 8 · 12.1%

Inulin and oligofructose 15 g vs inulin and oligofructose 7.5 g daily

Clinical remission · Patients with active mild to moderate ulcerative colitis

It is very uncertain whether inulin and oligofructose 15 g changes clinical remission (9 weeks) compared with inulin and oligofructose 7.5 g daily (very low certainty).

1 finding from 1 review

Probiotics vs placebo

Maintenance of clinical remission · Patients with quiescent ulcerative colitis

It is very uncertain whether probiotics changes maintenance of clinical remission (52 weeks) compared with placebo (very low certainty).

1 finding from 1 review

Oral 5‐ASA vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Failure to induce global or clinical remission · Patients with active mild to moderate ulcerative colitis

Oral 5‐ASA showed no clear difference in failure to induce global or clinical remission compared with comparator 5‐ASA (moderate certainty).

1 finding from 1 review

Etrolizumab vs placebo

Failure to induce clinical remission at end of study · patients with induction of remission in ulcerative colitis

Etrolizumab probably leads to lower failure to enter clinical remission at week 10 compared with placebo (moderate certainty).

2 findings from 1 review

Probiotic + 5‐aminosalicylic acid (5‐ASA) (mesalazine) vs 5‐aminosalicylic acid (5‐ASA) (mesalazine)

Maintenance of clinical remission · Patients with quiescent ulcerative colitis

Probiotic + 5‐aminosalicylic acid (5‐ASA) (mesalazine) showed no clear difference in maintenance of clinical remission (24 to 52 weeks) compared with 5‐ASA (mesalazine) (low certainty).

1 finding from 1 review