Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Day 3 vs Day 2 embryo transfer following IVF or ICSI

Clinical pregnancy rate · Women undergoing in vitro fertilisation or intracytoplasmic sperm injection

It is very uncertain whether day 3 changes clinical pregnancy rate per woman compared with day 2 embryo transfer following IVF or ICSI (very low certainty).

1 finding from 1 review

Day three versus day two embryo transfer following in vitro fertilization or intracytoplasmic sperm injection 2016 · Cochrane Headline outcomes only
RR 1.08 [0.98, 1.19]
12 studies · 2461 participants
Very low

Assisted hatching vs no assisted hatching

Clinical pregnancy rate · women undergoing assisted reproduction

Assisted hatching may leads to higher clinical pregnancy rate per woman randomised compared with no assisted hatching (low certainty).

1 finding from 1 review

Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)) 2021 · Cochrane Headline outcomes only
OR 1.2 [1.09, 1.33]
39 studies · 7249 participants
Low

GnRHa depot vs GnRHa daily injection

Clinical pregnancy rate · women undergoing pituitary suppression in assisted reproduction

GnRHa depot showed no clear difference in clinical pregnancy rate per woman Identified by the presence of a… compared with gnRHa daily injection (moderate certainty).

1 finding from 1 review

Depot versus daily administration of gonadotrophin‐releasing hormone agonist protocols for pituitary down regulation… 2013 · Cochrane Headline outcomes only
OR 0.96 [0.75, 1.23]
11 studies · 1259 participants
Moderate