Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 2 · 25%Very low 0 · 0%Low 3 · 37.5%Moderate 3 · 37.5%High 0 · 0%

NIPPV vs NCPAP

Chronic lung disease · )

Nasal intermittent positive pressure ventilation (NIPPV) may leads to lower chronic lung disease compared with nasal continuous positive airway pressure (NCPAP) (by population) (low certainty).

1 finding from 1 review

Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure… 2023 · Cochrane Headline outcomes only
RR 0.7 [0.52, 0.92]
12 studies · 1284 participants
Low

NIPPV vs NCPAP

Chronic lung disease · preterm neonates after extubation

Nasal intermittent positive pressure ventilation (NIPPV) showed no clear difference in chronic lung disease (oxygen supplementation at 36 weeks) compared with nasal continuous positive airway pressure (NCPAP) (moderate certainty).

1 finding from 1 review

Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for… 2023 · Cochrane Headline outcomes only
RR 0.93 [0.84, 1.05]
9 studies · 2001 participants
Moderate

nHFV vs NIPPV or NIV

Chronic lung disease · preterm infants with respiratory distress for initial respiratory support

nHFV may leads to lower chronic lung disease compared with nIPPV used (low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.63 [0.42, 0.95]
5 studies · 307 participants
Low

nHFV vs NIPPV or NIV

Chronic lung disease · ventilated preterm infants with planned extubation

nHFV showed no clear difference in chronic lung disease compared with nIPPV (moderate certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.88 [0.75, 1.04]
4 studies · 1236 participants
Moderate

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Chronic lung disease · ventilated preterm infants with failure of initial non‐invasive respiratory support

nHFV showed no clear difference in chronic lung disease compared with nIPPV following failure of initial non‐invasive respiratory support (low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 1.01 [0.7, 1.47]
1 study · 39 participants
Low

nHFV vs NIPPV or NIV

Death or chronic lung disease · preterm infants with respiratory distress for initial respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

nHFV vs NIPPV or NIV

Death or chronic lung disease · ventilated preterm infants with planned extubation

nHFV showed no clear difference in death or chronic lung disease compared with nIPPV (moderate certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.92 [0.79, 1.08]
3 studies · 1070 participants
Moderate

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Death or chronic lung disease · ventilated preterm infants with failure of initial non‐invasive respiratory support

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported