Findings

What do systematic reviews say?

7 questions · 7 findings · 5 reviews · Headline outcomes only

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No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 2 · 28.6%High 0 · 0%

Starches vs crystalloid

All‐cause mortality (at 90 days)

Starches showed no clear difference in all‐cause mortality (at 90 days) compared with crystalloid (moderate certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 1.01 [0.9, 1.14]
15 studies · 10415 participants
Moderate

Starches vs crystalloid

All‐cause mortality (within 30 days)

Starches showed no clear difference in all‐cause mortality (within 30 days) compared with crystalloid (moderate certainty).

1 finding from 1 review

Colloids versus crystalloids for fluid resuscitation in critically ill people 2018 · Cochrane Headline outcomes only
RR 0.99 [0.9, 1.09]
11 studies · 10135 participants
Moderate

Intervention not reported

All‐cause mortality (within 30 days) · adults undergoing cardiac surgery under general anaesthesia

The intervention showed no clear difference in all‐cause mortality (within 30 days) (low certainty).

1 finding from 1 review

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery 2019 · Cochrane Headline outcomes only
RR 0.95 [0.47, 1.9]
29 studies · 4099 participants
Low

Perioperative beta‐blockers vs placebo or usual care

Early all‐cause mortality (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers showed no clear difference in early all‐cause mortality (within 30 days) compared with placebo or standard care (low certainty).

1 finding from 1 review

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac… 2019 · Cochrane Headline outcomes only
RR 1.17 [0.89, 1.54]
16 studies · 11446 participants
Low

Nitroglycerin vs no treatment

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with no treatment (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.87]
1 study · 60 participants
Very low

Nitroglycerin vs placebo

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with placebo (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 2.81 [0.12, 63.83]
2 studies · 89 participants
Very low

Summary of findings table ‐ Platelet transfusion vs no platelet transfusion

All‐cause mortality up to 30 days after the procedure · thrombocytopenia

The review found no eligible studies for this question.

1 finding from 1 review

Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found