What do systematic reviews say?

iMRI image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

5‐ALA image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Neuronavigation image‐guided surgery vs surgery

The review found no eligible studies for this question.

• Intraoperative imaging technology to maximise extent of resection for glioma: a network meta‐analysis 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Intraoperative imaging technology to maximise extent of resection for glioma 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin vs clomiphene

The review found no eligible studies for this question.

• Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Skim milk enriched with GMP/G600 vs skim milk & lactose powder

Skim milk enriched with GMP/G600 showed no clear difference in study withdrawals due to adverse events compared with skim milk, plus lactose powder (low certainty).

• Dietary supplements for chronic gout 2021 · Cochrane Headline outcomes only
  RR 1.27 [0.53, 3.03]
  1 study · 120 participants
  Low
• Lifestyle interventions for chronic gout 2013 · Cochrane Headline outcomes only
  RR 1.27 [0.53, 3.03]
  1 study · 120 participants
  Low

Metformin combined with clomiphene citrate vs clomiphene

Metformin combined with clomiphene citrate probably leads to higher adverse events (gastrointestinal) per woman compared with clomiphene citrate alone (moderate certainty).

• Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome 2019 · Cochrane Headline outcomes only
  OR 4.26 [2.83, 6.4]
  6 studies · 852 participants
  Moderate
• Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with polycystic ovary… 2017 · Cochrane Headline outcomes only
  OR 3.97 [2.59, 6.08]
  3 studies · 591 participants
  Moderate

CBT vs TAU

• Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported
• Psychological therapies delivered remotely for the management of chronic pain (excluding headache) in adults 2023 · Cochrane Headline outcomes only
  RR 6 [2.2, 16.4]
  1 study · 140 participants
  Very low
• Psychological therapies for the management of chronic pain (excluding headache) in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1314 participants
  Very low