Findings

What do systematic reviews say?

4 questions · 4 findings · 4 reviews · Acute Respiratory Infections

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 0 · 0%Moderate 3 · 75%High 0 · 0%

Corticosteroids vs placebo

Adverse events · patients with sore throat

Corticosteroids showed no clear difference in adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids as standalone or add‐on treatment for sore throat 2020 · Cochrane Headline outcomes only
RR 1.08 [0.31, 3.77]
2 studies · 690 participants
Moderate

Oral corticosteroids vs placebo or NSAID

Adverse events · patients with acute sinusitis

1 finding from 1 review

Systemic corticosteroids for acute sinusitis 2014 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1193 participants
Moderate

Intervention not reported

Adverse events ‐ recurrent fever · acute bacterial meningitis

The intervention probably leads to higher adverse events ‐ recurrent fever (moderate certainty).

1 finding from 1 review

Corticosteroids for acute bacterial meningitis 2015 · Cochrane Headline outcomes only
RR 1.27 [1.09, 1.47]
12 studies · 1723 participants
Moderate

Corticosteroids vs no corticosteroid use

Number and nature of adverse events secondary to corticosteroid use (hospital‐acquired infection) · individuals with influenza

It is very uncertain whether corticosteroid therapy changes number and nature of adverse events secondary to corticosteroid use… compared with no corticosteroid therapy (very low certainty).

1 finding from 1 review

Corticosteroids as adjunctive therapy in the treatment of influenza 2019 · Cochrane Headline outcomes only
OR 2.74 [1.51, 4.95]
7 studies · 6114 participants
Very low