Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

11 questions · 11 findings · 5 reviews · Hepato-Biliary

No studies found 2 · 18.2%GRADE not reported 1 · 9.1%Very low 6 · 54.5%Low 1 · 9.1%Moderate 1 · 9.1%High 0 · 0%

Sclerotherapy vs no intervention

Serious adverse events and liver‐related morbidity: incidence of gastric varices · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

It is very uncertain whether sclerotherapy changes serious adverse events and liver‐related morbidity: incidence of… compared with no intervention (very low certainty).

1 finding from 1 review

Sclerotherapy vs no intervention

Serious adverse events and liver‐related morbidity: incidence of bleeding from gastric varices · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

It is very uncertain whether sclerotherapy changes serious adverse events and liver‐related morbidity: incidence of… compared with no intervention (very low certainty).

1 finding from 1 review

Carvedilol vs beta‐blocker

Non‐serious adverse events · adults with cirrhosis and gastroesophageal varices

It is very uncertain whether carvedilol changes non‐serious adverse events compared with traditional, non‐selective beta‐blockers (very low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Adverse events considered non‐serious · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

The review found no eligible studies for this question.

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).

1 finding from 1 review

Sclerotherapy vs no intervention

Serious adverse events and liver‐related morbidity: incidence of congestive hypertensive gastropathy · primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis

It is very uncertain whether sclerotherapy changes serious adverse events and liver‐related morbidity: incidence of… compared with no intervention (very low certainty).

1 finding from 1 review

Surgical portosystemic shunts vs devascularisation with splenectomy

Serious adverse events · people with hepatosplenic schistosomiasis

It is very uncertain whether surgical portosystemic shunts changes serious adverse events compared with devascularisation with splenectomy (very low certainty).

1 finding from 1 review