Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 6 reviews · Heart

No studies found 4 · 33.3%GRADE not reported 0 · 0%Very low 4 · 33.3%Low 3 · 25%Moderate 1 · 8.3%High 0 · 0%

Higher polyunsaturated fatty acid (PUFA) vs lower PUFA

Major adverse cardiac and cerebrovascular events · people with or without existing CVD, men and women

It is very uncertain whether higher polyunsaturated fatty acid (PUFA) changes major adverse cardiac and cerebrovascular events compared with lower PUFA (very low certainty).

1 finding from 1 review

Lidocaine vs disopyramide

Adverse events (AEs; adverse drug reaction): cardiac blocks (high‐degree atrioventricular block and bundle) · patients with myocardial infarction

It is very uncertain whether lidocaine changes adverse events (AEs; adverse drug reaction): cardiac blocks… compared with disopyramide (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse events ‐ myopathy · people with cardiovascular disease or at high risk of cardiovascular disease

It is very uncertain whether the intervention changes adverse events ‐ myopathy (very low certainty).

1 finding from 1 review

Intervention not reported

Major adverse cardiovascular events (MACE) · people with cardiovascular disease or at high risk of cardiovascular disease

The intervention probably leads to lower major adverse cardiovascular events (MACE) (moderate certainty).

1 finding from 1 review