Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews · Pain, Palliative and Supportive Care

No studies found 1 · 14.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 2 · 28.6%High 0 · 0%

Incidence of adverse events within 30 days of surgery · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Liposomal bupivacaine infiltration at the surgical site for the management of postoperative pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 583 participants
Moderate

Incidence of adverse events within 30 days of surgery · aged 18 years and older undergoing elective surgery at any surgical site

1 finding from 1 review

Incidence of adverse events within 30 days of surgery · adults aged ≥ 18 years undergoing elective surgery at any surgical site

The review found no eligible studies for this question.

1 finding from 1 review

Liposomal bupivacaine peripheral nerve block for the management of postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Low

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

Ibuprofen probably leads to lower adverse events (reported in the first 7 days after the procedure) compared with morphine (moderate certainty).

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
RR 0.58 [0.4, 0.83]
1 study · 154 participants
Moderate

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Adverse events (reported in the first 7 days after the procedure) · children with acute postoperative pain

Ibuprofen showed no clear difference in adverse events (reported in the first 7 days after the procedure) compared with placebo (low certainty).

1 finding from 1 review

Ibuprofen for acute postoperative pain in children 2024 · Cochrane Headline outcomes only
RR 0.79 [0.51, 1.23]
5 studies · 384 participants
Low