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Evidence found and GRADE certainty

6 questions · 6 findings · 2 reviews · Oral medicine and oral cancer

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No studies found 1 · 16.7%GRADE not reported 4 · 66.7%Very low 1 · 16.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Chlorhexidine + zinc acetate mouthwash vs Placebo mouthwash

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 3 months
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

0.05% chlorhexidine + 0.05% cetylpyridinium chloride + 0.14% zinc lactate mouthrinse vs Placebo mouthwash

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 2 weeks
    Adverse events (Table 6). Risk with placebo mouthwash: None reported. Risk with halita mouthwash: tongue staining was seen in patients who gargled, rather than rinsed. 40 participants (1 RCT). Certainty: VERY LOW.
    1 study · 40 participants
    Very low

0.05% chlorhexidine + 0.05% cetylpyridinium chloride + 0.14% zinc lactate mouthrinse vs placebo

Adverse events (tongue and tooth staining) · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or…
1 finding from 1 review
  • Mouthrinses for the treatment of halitosis 2008 · Cochrane All outcomes
    2 weeks
    Winkel 2003: significantly more tongue staining (P < 0.001) and tooth staining (P < 0.002) were noted with the chlorhexidine + cetylpyridinium chloride + zinc lactate mouthrinse than with placebo.
    1 study · 40 participants
    GRADE not reported

Topical G32 (ayurvedic preparation) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    1 week
    Patil 2017 reported burning mucosa and drying of mouth in a few subjects using the control drug (chlorhexidine) and no adverse effects were reported in the intervention group (G32 tablets).
    1 study · 40 participants
    GRADE not reported

Chlorine dioxide mouthrinse (with tongue scraping) vs Chlorhexidine mouthwash (with tongue scraping)

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    1 week
    Wirthlin 2011 reported altered taste sensation as the adverse event. OLT scores could not be included in the analysis as the group-wise data were not given.
    1 study · 22 participants
    GRADE not reported