Question · asked by 1 review
0.05% chlorhexidine + 0.05% cetylpyridinium chloride + 0.14% zinc lactate mouthrinse vs Placebo mouthwash: Adverse events
- Population
- Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological halitosis, non-oral halitosis, and severe chronic periodontitis (clinical attachment level 5 mm or more)
- Intervention
- 0.05% chlorhexidine + 0.05% cetylpyridinium chloride + 0.14% zinc lactate mouthrinse
- Comparison
- Placebo mouthwash
- Outcome
- Adverse events
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Halita mouthwash (chlorhexidine 0.05% + cetylpyridinium chloride 0.05% + zinc lactate 0.14%) vs Placebo mouthwash Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced… · mean 2 weeks Interventions for managing halitosis (2019) · Cochrane All outcomes | Adverse events (Table 6). Risk with placebo mouthwash: None reported. Risk with halita mouthwash: tongue staining was seen in patients who gargled, rather than rinsed. 40 participants (1 RCT). Certainty: VERY LOW. | 1 study · 40 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for managing halitosis 2019 · Cochrane All outcomes | 2019-04 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.