Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

20 questions · 20 findings · 8 reviews

No studies found 5 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 35%Moderate 4 · 20%High 4 · 20%

Allopurinol vs placebo

Serious adverse events · people with chronic gout

Allopurinol showed no clear difference in serious adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Allopurinol vs benzbromarone

Withdrawals due to adverse events · people with chronic gout

Allopurinol showed no clear difference in withdrawal due to adverse events compared with benzbromarone (low certainty).

1 finding from 1 review

Allopurinol vs placebo

Withdrawals due to adverse events · people with chronic gout

Allopurinol showed no clear difference in withdrawal due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs allopurinol

Serious adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in serious Adverse Events compared with allopurinol (moderate certainty).

1 finding from 1 review

Benzbromarone vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Benzbromarone showed no clear difference in withdrawal due to adverse events compared with allopurinol (low certainty).

1 finding from 1 review

Febuxostat 40 mg/day vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Febuxostat 40 mg/day showed no clear difference in discontinuations due to adverse events compared with allopurinol (high certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in discontinuations due to adverse events compared with allopurinol (moderate certainty).

1 finding from 1 review

Febuxostat 120 mg/day vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Febuxostat 120 mg/day showed no clear difference in discontinuations due to adverse events compared with allopurinol (high certainty).

1 finding from 1 review