evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

419 questions · 420 findings · 128 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 71 · 16.9%GRADE not reported 69 · 16.4%Very low 96 · 22.9%Low 116 · 27.6%Moderate 63 · 15%High 5 · 1.2%

MDAC + hospital intervention vs SDAC + hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (carbamazepine, yellow oleander, or combinations of different drugs)

MDAC + hospital intervention may leads to higher incidence of adverse events compared with SDAC + hospital intervention (low certainty).

1 finding from 1 review

SDAC vs syrup of ipecac

Incidence of adverse events · first aid in patients with acute oral poisoning (anti‐inflammatory drugs, analgesics or psychotropic drugs)

It is very uncertain whether SDAC changes incidence of adverse events compared with syrup of ipecac (very low certainty).

1 finding from 1 review

MDAC + hospital intervention vs hospital intervention

Incidence of adverse events · first aid in patients with acute oral poisoning (benzodiazepines, yellow oleander or combinations of different drugs)

MDAC + hospital intervention showed no clear difference in incidence of adverse events compared with hospital intervention (low certainty).

1 finding from 1 review

CBT vs alternative treatment

Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
  • Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomes
    SoF: 3 studies reported minor adverse events in the control group; 1 study reported minor adverse events in psychological therapy group; 1 study reported that there were no adverse events. Results: NCT00066937 minor…
    5 studies
    Very low

Mechanical tongue cleaning (tongue scraper) vs No tongue cleaning

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 2 weeks
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

Hinokitiol gel vs Placebo gel

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 4 weeks
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

Chlorhexidine + zinc acetate mouthwash vs Placebo mouthwash

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 3 months
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

1000 mg champignon extract vs placebo

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

The review found no eligible studies for this question.

1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 2 weeks
    Adverse events: listed in the Summary of findings table but no data reported. No data were reported for adverse events.
    0 studies
    No studies found

0.05% chlorhexidine + 0.05% cetylpyridinium chloride + 0.14% zinc lactate mouthrinse vs Placebo mouthwash

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 2 weeks
    Adverse events (Table 6). Risk with placebo mouthwash: None reported. Risk with halita mouthwash: tongue staining was seen in patients who gargled, rather than rinsed. 40 participants (1 RCT). Certainty: VERY LOW.
    1 study · 40 participants
    Very low

Halita mouthrinse vs Perio-plus mouthrinse

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    mean 8 days
    Adverse events (Table 12). Risk with Perio-plus mouthrinse: 1 patient reported unpleasant feeling after the use of the product; there were no severe adverse events reported. Risk with halita mouthrinse: 1 patient…
    1 study · 36 participants
    Very low

Topical G32 (ayurvedic preparation) vs Chlorhexidine, 0.2% to 2% (solution or gel)

Adverse events · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…
1 finding from 1 review
  • Interventions for managing halitosis 2019 · Cochrane All outcomes
    1 week
    Patil 2017 reported burning mucosa and drying of mouth in a few subjects using the control drug (chlorhexidine) and no adverse effects were reported in the intervention group (G32 tablets).
    1 study · 40 participants
    GRADE not reported