Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

230 questions · 231 findings · 98 reviews

No studies found 73 · 31.6%GRADE not reported 10 · 4.3%Very low 71 · 30.7%Low 50 · 21.6%Moderate 20 · 8.7%High 7 · 3%

Intervention not reported

Adverse events · Children receiving antibiotic treatment between 4 and 28 days duration for a variety of infections

The intervention showed no clear difference in adverse events (low certainty).

1 finding from 1 review

Band ligation vs no intervention or a sham procedure

Serious adverse events Idiopathic thrombocytopaenic purpura · children with portal hypertension and large oesophageal varices, without previous gastrointestinal bleeding or beta‐blocker treatment

It is very uncertain whether band ligation changes serious adverse events Idiopathic thrombocytopaenic purpura compared with sham or no intervention (very low certainty).

1 finding from 1 review