Question · asked by 1 review
Benzodiazepines vs phenobarbital (as active placebo): Adverse events: any
- Population
- patients with antipsychotic‐induced tardive dyskinesia
- Intervention
- Benzodiazepines
- Comparison
- phenobarbital (as active placebo)
- Outcome
- Adverse events: any
It is very uncertain whether benzodiazepines changes adverse events: any compared with phenobarbital (as active placebo) (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Benzodiazepines vs phenobarbital (as active placebo) Adverse events: any · psychiatric patients (mainly schizophrenia) with antipsychotic‐induced tardive dyskinesia It is very uncertain whether benzodiazepines changes adverse events: any compared with phenobarbital (as active placebo) (very low certainty). Benzodiazepines for antipsychotic‐induced tardive dyskinesia (2018) · Cochrane Headline outcomes only | RR 1.53 [0.97, 2.41] | 1 study · 21 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Benzodiazepines for antipsychotic‐induced tardive dyskinesia 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.