Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,199 questions · 1,226 findings · 451 reviews

No studies found 289 · 23.6%GRADE not reported 121 · 9.9%Very low 350 · 28.5%Low 279 · 22.8%Moderate 139 · 11.3%High 48 · 3.9%

Prebiotic vs placebo

Withdrawals due to adverse events · people with histologically confirmed diagnosis of ulcerative colitis in remission

It is very uncertain whether prebiotics changes withdrawals due to adverse events (60 days to 6 months) compared with placebo (very low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) vs phosphodiesterase type 5 inhibitors

Minor adverse events · erectile dysfunction in men with obstructive sleep apnoea

It is very uncertain whether continuous positive airway pressure (CPAP) changes minor adverse events compared with phosphodiesterase type 5 inhibitors (very low certainty).

1 finding from 1 review

Prebiotic vs placebo

Withdrawals due to adverse events · people with mild‐to‐moderate disease (Rachmilewitz index) or active disease (SCCAI score of 4 to 10)

It is very uncertain whether prebiotics changes withdrawals due to adverse events (14 days to 2 or 3 months) compared with placebo (very low certainty).

1 finding from 1 review