Summary of findings. Bandage vs cast
Serious adverse events (3 to 4 weeks · children with stable wrist fracture, predominantly buckle (torus) fracturesa
1 finding from 1 review
- no estimate extracted2 studies · 139 participantsGRADE not reported
Findings
What do systematic reviews say?
1,228 questions · 1,245 findings · 383 reviews
No studies found 403 · 32.4%GRADE not reported 128 · 10.3%Very low 385 · 30.9%Low 232 · 18.6%Moderate 81 · 6.5%High 16 · 1.3%
Magnesium citrate vs placebo
Risk of adverse events: Loose stools · participants at risk of high altitude illness
Magnesium citrate may leads to higher risk of adverse events: Loose stools compared with placebo (low certainty).
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes onlyRR 3.25 [1.17, 8.99]1 study · 70 participantsLow
A functional programme vs a stretching programme
Adverse events/serious adverse events · people with NMD
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for promoting physical activity in people with neuromuscular disease 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
A physical activity programme (weight‐bearing) vs no physical activity
Adverse events/serious adverse events · people with NMD
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for promoting physical activity in people with neuromuscular disease 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
A sensor‐based, interactive exercise programme vs no sensor‐based, interactive exercise programme
Adverse events/serious adverse events · people with NMD
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for promoting physical activity in people with neuromuscular disease 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Alarm vs miscellaneous treatments
Proportion of children adverse events · children with nocturnal enuresis
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Physical activity advice plus placebo vs no physical activity advice plus placebo
Serious adverse events ‐ not reported · participants with quiescent IBD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Physical activity advice plus placebo vs no physical activity advice plus omega 3
Serious adverse events ‐ not reported · participants with quiescent IBD
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Spironolactone vs placebo
Risk of adverse events ‐ not reported · participants at risk of high altitude illness
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Acetazolamide vs spironolactone 100 mg
Risk of adverse events ‐ not reported · participants at risk of high altitude illness
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Sumatriptan vs placebo
Risk of adverse events ‐ not reported · participants at risk of high altitude illness
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Plate fixation vs tension band wiring
Adverse events ‐ delayed or non‐union · adults with olecranon fractures
It is very uncertain whether plate fixation changes adverse events ‐ delayed or non‐union compared with tension band wiring (very low certainty).
1 finding from 1 review
- Surgical interventions for treating fractures of the olecranon in adults 2014 · Cochrane Headline outcomes onlyRR 0.171 study · 41 participantsVery low
Intervention not reported
Serious adverse events ‐ not measured · patients with acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Intermittent oral vs oral calcitriol
Adverse events ‐ Calcium > 11.5 mg/dL · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
- Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 80 participantsModerate
Early vs delayed mobilisation
Adverse events: Shoulder complications · adults with minimally displaced or displaced (2‐part or 3‐part) proximal humeral fractures treated non‐surgically (5 trials)
1 finding from 1 review
- Interventions for treating proximal humeral fractures in adults 2022 · Cochrane Headline outcomes onlyno estimate extracted4 studies · 259 participantsVery low
An extended NVP plus ZDV dual regimen administered to infants for 14 weeks vs sdNVP plus ZDV (1 week)
Infants with Severe Adverse Events · Breastfeeding infants of HIV‐infected mothers
It is very uncertain whether an extended NVP plus ZDV regimen administered to infants for 14 weeks changes infants with any Severe Adverse Events compared with sdNVP plus ZDV (1 week) (very low certainty).
1 finding from 1 review
- Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes onlyRR 1.75 [1.22, 2.53]1 study · 2000 participantsVery low
An extended NVP plus ZDV dual regimen administered to infants for 14 weeks vs an extended NVP regimen administered to infants
Infants with Severe Adverse Events · Breastfeeding infants of HIV‐infected mothers
An extended NVP plus ZDV dual regimen administered to infants for 14… may leads to higher infants with any Severe Adverse Events compared with an extended NVP regimen administered to infants (low certainty).
1 finding from 1 review
- Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes onlyRR 1.66 [1.16, 2.37]1 study · 2013 participantsLow
Intervention not reported
Harms or adverse events ‐ not reported · patients and carers
The review found no eligible studies for this question.
1 finding from 1 review
- Information interventions for orienting patients and their carers to cancer care facilities 2011 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Intraperitoneal vs oral calcitriol
Adverse events ‐ Phosphate > 7.0 mg/dL · patients with bone disease in children with chronic kidney disease
1 finding from 1 review
- Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes onlyno estimate extracted1 study · 33 participantsLow
Fexofenadine 120 mg/d vs placebo (1‐week intervention)
Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema
Fexofenadine 120 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (1‐week intervention) (moderate certainty).
1 finding from 1 review
- Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes onlyRR 1.05 [0.74, 1.5]1 study · 411 participantsModerate