Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

49 questions · 51 findings · 25 reviews

No studies found 16 · 31.4%GRADE not reported 2 · 3.9%Very low 18 · 35.3%Low 9 · 17.6%Moderate 3 · 5.9%High 3 · 5.9%

Combined steroid and antibiotic therapy vs antibiotics alone

Adverse events at 3 to 12 months' · eyes with acute endophthalmitis following an intraocular procedure (e.g. surgery, intravitreous injection)

Combined steroid and antibiotic therapy showed no clear difference in adverse events at 3 to 12 months' compared with antibiotics alone (low certainty).

1 finding from 1 review

E1B‐deleted (dl1520) adenovirus vs percutaneous alcohol injection

Adverse events considered non‐serious · participants with unresectable hepatocellular carcinoma

It is very uncertain whether E1B‐deleted (dl1520) adenovirus changes adverse events considered non‐serious (number of participants) compared with percutaneous ethanol injection (very low certainty).

1 finding from 1 review

Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound

Adverse events (partial loss of movement, algodystrophic syndrome) · patients with trigger finger

It is very uncertain whether open surgery changes adverse events (partial loss of movement, algodystrophic syndrome) compared with steroid injection plus hyaluronic acid injection guided by ultrasound (very low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Adverse events (infection, tendon or pulley injury, flare, cutaneous discomfort, fat necrosis) · patients with trigger finger

Open surgery showed no clear difference in adverse events (infection, tendon or pulley injury, flare, cutaneous… compared with steroid injection (low certainty).

1 finding from 1 review

Percutaneous surgery vs steroid injection

Adverse events (infection, partial loss of movement, tendon or −0 injury, dysaesthesia, and skin atrophy or hypopigmentation) · patients with trigger finger

It is very uncertain whether percutaneous surgery changes adverse events (infection, partial loss of movement, tendon or −0… compared with steroid injection (very low certainty).

1 finding from 1 review