Findings

What do systematic reviews say?

1,041 questions · 1,056 findings · 283 reviews

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No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Physical activity advice plus placebo vs no physical activity advice plus omega 3

Adverse events: · participants with quiescent IBD

1 finding from 1 review

Interventions for fatigue in inflammatory bowel disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Botulinum toxin vs observation

Adverse events. · people with sixth nerve palsy

1 finding from 1 review

Interventions for eye movement disorders due to acquired brain injury 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 47 participants
Low

Circumcision plus usual care vs Waitlist/Usual Care

Adverse events3 · participants with chronic prostatitis/chronic pelvic pain syndrome

Circumcision plus usual care showed no clear difference in adverse events3 compared with waiting list plus usual care (low certainty).

1 finding from 1 review

Non‐pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2018 · Cochrane Headline outcomes only
RR 1.23 [0.86, 1.76]
1 study · 713 participants
Low

Spinal manipulative therapy vs inert interventions

Serious adverse events · Patients with acute low‐back pain

1 finding from 1 review

Spinal manipulative therapy for acute low‐back pain 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
GRADE not reported

Spinal manipulative therapy vs other interventions

Serious adverse events · Patients with acute low‐back pain

1 finding from 1 review

Spinal manipulative therapy for acute low‐back pain 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
GRADE not reported

Modafinil vs placebo

Adverse events ( · people with a primary brain tumour

It is very uncertain whether boele 2013: modafinil changes adverse events ( compared with placebo (very low certainty).

1 finding from 1 review

Interventions for the management of fatigue in adults with a primary brain tumour 2022 · Cochrane Headline outcomes only
RR 2.79 [0.59, 13.16]
1 study · 37 participants
Very low

Personalised intervention vs non‐personalised intervention

Any adverse events · subgroups of children with conduct problems

The review found no eligible studies for this question.

1 finding from 1 review

Personalised interventions for subgroups of children with conduct problems 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Any adverse events · informal caregivers of people affected by cancer

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Any adverse events · individuals with cancer (patients)

The review found no eligible studies for this question.

1 finding from 1 review

Psychosocial interventions for informal caregivers of people living with cancer 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Simplified vs usual regimens

All adverse events · people with asthma

Simplified showed no clear difference in all adverse events compared with usual regimens (low certainty).

1 finding from 1 review

Interventions to improve adherence to inhaled steroids for asthma 2017 · Cochrane Headline outcomes only
OR 0.76 [0.56, 1.04]
1 study · 1233 participants
Low

Intervention not reported

Adverse drug events · older people (aged 65 years or older) living in care homes

1 finding from 1 review

Interventions to optimise prescribing for older people in care homes 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1228 participants
Low

Surgical thrombectomy vs mechanical thrombectomy

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes major adverse events compared with mechanical thrombectomy (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 1.98 [0.78, 5.03]
3 studies · 404 participants
Very low

Surgical thrombectomy vs mechanical thrombectomy

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes minor adverse events compared with mechanical thrombectomy (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 0.89 [0.54, 1.48]
3 studies · 404 participants
Very low

Mechanical thrombectomy vs pulse spray technique

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether mechanical thrombectomy changes major adverse events compared with pulse spray technique (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 1.26 [0.54, 2.92]
3 studies · 372 participants
Very low

Mechanical thrombectomy vs pulse spray technique

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether mechanical thrombectomy changes minor adverse events compared with pulse spray technique (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 0.7 [0.1, 4.98]
2 studies · 252 participants
Very low

Mechanical thrombectomy vs continuous infusion

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mechanical thrombectomy vs continuous infusion

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether mechanical thrombectomy changes minor adverse events compared with continuous infusion (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 0.32 [0.09, 1.16]
2 studies · 118 participants
Very low

Surgical thrombectomy vs continuous infusion

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes major adverse events compared with continuous infusion (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 0.13 [0.01, 2.4]
1 study · 31 participants
Very low

Surgical thrombectomy vs continuous infusion

Minor adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

It is very uncertain whether surgical thrombectomy changes minor adverse events compared with continuous infusion (very low certainty).

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
RR 0.19 [0.02, 1.43]
1 study · 31 participants
Very low

Continuous infusion vs pulse spray technique

Major adverse events · thrombosed haemodialysis arteriovenous fistulas and grafts

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for thrombosed haemodialysis arteriovenous fistulas and grafts 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found