Low‐dose colchicine vs NSAIDs
Serious adverse events · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
458 questions · 473 findings · 205 reviews
No studies found 128 · 27.1%GRADE not reported 49 · 10.4%Very low 142 · 30%Low 106 · 22.4%Moderate 36 · 7.6%High 12 · 2.5%
Low‐dose colchicine vs placebo
Serious adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 133 participantsGRADE not reported
Summary of findings. Below‐elbow vs above‐elbow cast
Serious adverse events ( · children with either displaced distal radius fracture with intact or displaced ulna fracture (both‐bone fracture), or minimally displaced…
1 finding from 1 review
- no estimate extracted2 studies · 215 participantsGRADE not reported
Low‐dose colchicine vs NSAIDs
Withdrawals due to adverse events · acute gout
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Low‐dose colchicine vs placebo
Withdrawals due to adverse events · acute gout
1 finding from 1 review
- no estimate extracted1 study · 133 participantsGRADE not reported
Low‐dose colchicine vs NSAIDs
Number of participants reporting an adverse event · acute gout
Low‐dose colchicine showed no clear difference in total number of participants reporting adverse events compared with NSAIDs (low certainty).
1 finding from 1 review
- RR 1.07 [0.88, 1.29]1 study · 399 participantsLow
Low GI vs high GI
Adverse events · Adults with coronary heart disease
The review found no eligible studies for this question.
1 finding from 1 review
- Low glycaemic index diets for the prevention of cardiovascular disease 2017 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
HFNC vs standard oxygen therapy
Adverse events · infants with bronchiolitis
Summary of findings table ‐ High‐flow nasal cannula showed no clear difference in adverse events compared with standard oxygen therapy (low‐flow) (low certainty).
1 finding from 1 review
- High‐flow nasal cannula therapy for infants with bronchiolitis 2024 · Cochrane Headline outcomes onlyRR 1.2 [0.38, 3.74]4 studies · 1789 participantsLow
HFNC vs low flow nasal cannula (LFNC)
Adverse events · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review
- High flow nasal cannula for respiratory support in term infants 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 95 participantsGRADE not reported
Dexamethasone vs placebo
Adverse events: General‐ Follow‐ up: From arrival to 24 hours later · participants at risk of high altitude illness
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs 2017 · Cochrane Headline outcomes onlyno estimate extracted1 study · 21 participantsVery low
Acetazolamide vs placebo
Adverse events: Paresthesias‐ Follow‐ up: From arrival to 24 hours later · participants at risk of high altitude illness
Acetazolamide may leads to higher adverse events: Paresthesias‐ Follow‐ up: From arrival to 24 hours… compared with placebo (low certainty).
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs 2017 · Cochrane Headline outcomes onlyRR 5.53 [2.81, 10.88]5 studies · 789 participantsLow
Acetazolamide vs placebo
Side effects or other adverse events · participants at risk of high altitude illness
Acetazolamide may leads to higher adverse events: side effects‐ Follow‐ up: From arrival to 24 hours… compared with placebo (low certainty).
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs 2017 · Cochrane Headline outcomes onlyRR 2.19 [1.36, 3.53]1 study · 400 participantsLow
Budesonide vs placebo
Side effects or other adverse events · participants at risk of high altitude illness
1 finding from 1 review
- Interventions for preventing high altitude illness: Part 1. Commonly‐used classes of drugs 2017 · Cochrane Headline outcomes onlyno estimate extracted1 study · 40 participantsVery low
Low GI vs high GI
Adverse eventsMeasurement unclear · overweight or obese adults
1 finding from 1 review
- Low glycaemic index diets for the prevention of cardiovascular disease 2017 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 38 participantsLow
Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension
Adverse events · patients with adhesive capsulitis (frozen shoulder)
Combination of manual therapy and exercise following joint distension leads to lower adverse events compared with sham ultrasound following joint distension (high certainty).
1 finding from 1 review
- Manual therapy and exercise for adhesive capsulitis (frozen shoulder) 2014 · Cochrane Headline outcomes onlyRR 0.991 study · 149 participantsHigh
Low‐pressure vs standard pressure pneumoperitoneum
Serious adverse events · patients with laparoscopic cholecystectomy.
It is very uncertain whether low pressure changes serious adverse events compared with standard pressure pneumoperitoneum (very low certainty).
1 finding from 1 review
- Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy 2014 · Cochrane Headline outcomes onlyRR 3 [0.14, 65.9]7 studies · 394 participantsVery low
Supervised maintenance programme following pulmonary rehabilitation vs usual care
Adverse events · patients with chronic obstructive pulmonary disease
1 finding from 1 review
- Supervised maintenance programmes following pulmonary rehabilitation compared to usual care for chronic obstructive… 2021 · Cochrane Headline outcomes onlyno estimate extracted24 participantsGRADE not reported
Comparison 2: 2 days oral amoxicillin + injectable gentamicin followed by 5 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin
Adverse events · neonates with possible serious bacterial infection
1 finding from 1 review
- Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes onlyno estimate extracted1 study · 893 participantsHigh
Comparison 2: 2 days injectable benzylpenicillin + injectable gentamicin followed by 5 days oral amoxicillin vs 7 days injectable benzylpenicillin + injectable gentamicin
Adverse events · neonates with possible serious bacterial infection
Comparison 2: 2 days injectable benzylpenicillin + injectable… showed no clear difference in adverse events compared with 7 days injectable benzylpenicillin + injectable gentamicin (moderate certainty).
1 finding from 1 review
- Community‐based antibiotic delivery for possible serious bacterial infections in neonates in low‐ and middle‐income… 2019 · Cochrane Headline outcomes onlyRR 1.39 [0.67, 2.87]3 studies · 2036 participantsModerate
Homocysteine‐lowering interventions (Folic Acid, Vitamin B6 and Vitamin B12) vs placebo or usual care
Adverse events · people with or without existing cardiovascular disease, men and women
Homocysteine‐lowering interventions (Vitamin B6 (pyridoxine;… showed no clear difference in adverse events compared with placebo or standard care (high certainty).
1 finding from 1 review
- Homocysteine‐lowering interventions for preventing cardiovascular events 2017 · Cochrane Headline outcomes onlyRR 1.07 [1, 1.14]8 studies · 35788 participantsHigh