Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,041 questions · 1,056 findings · 283 reviews

No studies found 346 · 32.8%GRADE not reported 111 · 10.5%Very low 326 · 30.9%Low 195 · 18.5%Moderate 66 · 6.3%High 12 · 1.1%

Zinc vs placebo

Adverse events · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)

It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes adverse events compared with placebo (very low certainty).

1 finding from 1 review

Acupuncture vs sham control

Adverse events · Patients with idiopathic dysgeusia and hypogeusia

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic appliances (palatal crib) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Adverse events · All patients with cancer who are receiving treatment
2 findings from 1 review

Psychological intervention + orthodontic treatment (palatal crib or palatal arch) vs no treatment

Adverse events · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review