Serious adverse events · postmenopausal women at lower risk of fractures1
Intermittent/cyclic etidronate 400 mg/day showed no clear difference in serious adverse events compared with placebo (moderate certainty).
1 finding from 1 review
RR 0.9 [0.52, 1.54]
Studies not reported
Moderate
Serious adverse events · patients on HD with HCV infection
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · postmenopausal women at lower risk of fractures1
It is very uncertain whether risedronate 5 mg/day changes serious adverse events compared with placebo (very low certainty).
1 finding from 1 review
RR 0.74 [0.42, 1.3]
Studies not reported
Very low
Serious adverse events · adults with olfactory dysfunction for ≥ 4 weeks following COVID‐19 infection
1 finding from 1 review
Serious adverse events · adults with olfactory dysfunction for ≥ 4 weeks following COVID‐19 infection
1 finding from 1 review
Serious adverse events · people with olfactory dysfunction for less than 4 weeks following COVID‐19 infection
1 finding from 1 review
Serious adverse events · acute gout
1 finding from 1 review
Serious adverse events · people with surgically‐induced remission in Crohn's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · children with acute asthma
1 finding from 1 review
Intervention not reported
Serious adverse events · adults with complex regional pain syndrome type 1 (lower limb)
1 finding from 1 review
no estimate extracted
20 participants
Very low
Surgically‐related severe adverse effects (grade 3+) ‐ postoperative G3+ events (within 30 days of surgery) · women with advanced ovarian epithelial cancer
Neoadjuvant chemotherapy prior to interval surgery (NACT) probably leads to lower surgically‐related severe adverse effects (grade 3+) ‐ postoperative… compared with surgery followed by chemotherapy (PDS) (moderate certainty).
1 finding from 1 review
Adverse events Â
1 finding from 1 review
Adverse events Adverse events included discomfort, local skin reactions, superficial infections, cold induced injuries and thrombolytic events · people undergoing total knee replacement
It is very uncertain whether any cold therapy changes total adverse eventsAdverse events included discomfort, local skin… compared with no cold therapy following total knee replacement (very low certainty).
1 finding from 1 review
Proportion of participants with 1 or more serious adverse events according to International Conference on Harmonisation Good Clinical Practice (ICH‐GCP) · adults admitted to the ICU
It is very uncertain whether higher changes proportion of participants with ≥ 1 serious adverse events according… compared with lower FiO2 or targets of arterial oxygenation (very low certainty).
1 finding from 1 review
Serious adverse events ( · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
1 finding from 1 review
Serious adverse events ( · adult patients with an implantable cardioverter defibrillator
It is very uncertain whether exercise changes serious adverse events ( compared with no exercise at longest available follow‐up (very low certainty).
1 finding from 1 review
Adverse effects: headache · women with endometriosis, following complete surgical excision of lesions
It is very uncertain whether raloxifene changes adverse events ‐ headache compared with placebo (very low certainty).
1 finding from 1 review
Adverse events ‐ migraine · women with endometriosis, following complete surgical excision of lesions
It is very uncertain whether raloxifene changes adverse events ‐ migraine compared with placebo (very low certainty).
1 finding from 1 review
Serious adverse events (N) · people at increased risk for developing type 2 diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events ‐ depression · women with endometriosis, following complete surgical excision of lesions
It is very uncertain whether raloxifene changes adverse events ‐ depression compared with placebo (very low certainty).
1 finding from 1 review