Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

891 questions · 902 findings · 317 reviews

No studies found 210 · 23.3%GRADE not reported 56 · 6.2%Very low 236 · 26.2%Low 220 · 24.4%Moderate 146 · 16.2%High 34 · 3.8%

Sclerotherapy vs placebo

Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins

Sclerotherapy probably leads to higher adverse events ‐ hyperpigmentation ( compared with placebo (moderate certainty).

1 finding from 1 review

Convective radiofrequency water vapour thermal therapy vs sham

Major adverse events · men with lower urinary tract symptoms suggesting benign prostatic hyperplasia

It is very uncertain whether convective radiofrequency water vapour thermal therapy changes major adverse events compared with sham procedure (very low certainty).

1 finding from 1 review

Radiotherapy vs botulinum toxin

Adverse events, reported as "negative experiences" · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

It is very uncertain whether radiotherapy changes adverse events, reported as "negative experiences" compared with botulinum toxin (very low certainty).

1 finding from 1 review