Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

12 questions · 12 findings · 12 reviews · Headline outcomes only

No studies found 4 · 33.3%GRADE not reported 0 · 0%Very low 4 · 33.3%Low 3 · 25%Moderate 1 · 8.3%High 0 · 0%

Whole‐facility changes: Home‐like models vs traditional environment

Serious adverse effects Physical restraints, reported as percentage points (lower = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings

It is very uncertain whether whole‐facility changes: Home‐like models changes serious adverse effects Physical restraints, reported as percentage… compared with traditional environment (very low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects · Various (pregnant women; daily smokers aged 16 and older; university students; children aged 5‐13)
1 finding from 1 review

Standard treatment plus systemic corticosteroids vs usual care

Adverse effects: exposure keratopathy · patients age 10 years and older with periorbital or orbital cellulitis

It is very uncertain whether standard treatment plus systemic corticosteroids changes adverse effects: exposure keratopathy compared with standard treatment alone (very low certainty).

1 finding from 1 review

Rice fortified with iron alone or in combination with other micronutrients vs unfortified rice (no micronutrients added)

Any adverse effects (hookworm infection risk) · general population of all age groups (including pregnant women) from any country, over two years of age

Rice fortified with iron alone or in combination with other… may leads to higher any adverse effects (hookworm infection risk) compared with unfortified rice (no micronutrients added) (low certainty).

1 finding from 1 review

Provision of maize flour or maize flour products fortified with iron plus other vitamins and minerals vs unfortified maize flours or maize flour products

Any adverse effects (including constipation, nausea, vomiting, heartburn or diarrhoea, as measured by trialists) · general population older than 2 years of age (including pregnant women), in Kenya and Mexico

The review found no eligible studies for this question.

1 finding from 1 review

Loratadine 10 mg vs placebo (4‐week intervention)

Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema

Loratadine 10 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (4‐week intervention) (low certainty).

1 finding from 1 review