What do systematic reviews say?

Any prophylaxis vs no prophylaxis

It is very uncertain whether any prophylaxis changes adverse effects compared with no prophylaxis (very low certainty).

• Interventions for preventing ophthalmia neonatorum 2020 · Cochrane Headline outcomes only
  OR 0.93
  1993 participants
  Very low

Intervention not reported

• Interventions for improving adherence to ocular hypotensive therapy 2013 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 650 participants
  Very low

Intervention not reported

The review found no eligible studies for this question.

• Interventions for improving adherence to ocular hypotensive therapy 2013 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Systemic tranexamic acid vs control

The review found no eligible studies for this question.

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Phototherapeutic keratectomy vs alcohol delamination

The review found no eligible studies for this question.

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Therapeutic contact lens vs topical lubrication

The review found no eligible studies for this question.

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Phototherapeutic keratectomy vs alcohol delamination

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 33 participants
  Very low

Diamond burr superficial keratectomy (after epithelial debridement) vs sham diamond burr (after epithelial debridement)

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Low

Therapeutic contact lens vs topical lubrication

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Systemic aminocaproic acid vs placebo

Systemic aminocaproic acid probably leads to higher adverse effects: nausea or vomiting compared with placebo (moderate certainty).

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  RR 8.6 [2.09, 35.5]
  3 studies · 131 participants
  Moderate

Topical aminocaproic acid vs placebo

The review found no eligible studies for this question.

• Medical interventions for traumatic hyphema 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgery vs botulinum neurotoxin injections

• Interventions for infantile esotropia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 101 participants
  Very low

Bilateral recession vs unilateral recession‐resection

• Interventions for infantile esotropia 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 118 participants
  Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

• Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 10 participants
  Very low

Diamond burr superficial keratectomy (after epithelial debridement) vs sham diamond burr (after epithelial debridement)

• Interventions for recurrent corneal erosions 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 48 participants
  Moderate