Findings

What do systematic reviews say?

72 questions · 79 findings · 22 reviews

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No studies found 48 · 60.8%GRADE not reported 11 · 13.9%Very low 0 · 0%Low 9 · 11.4%Moderate 11 · 13.9%High 0 · 0%

Inhalational anaesthesia vs intravenous anaesthesia

Adverse effects: IOP spikes · adults undergoing transabdominal robotic assisted laparoscopic surgery

1 finding from 1 review

Total intravenous anaesthesia versus inhalational anaesthesia for adults undergoing transabdominal robotic assisted… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 66 participants
Low

HES vs placebo or no treatment

Adverse effects · women at high risk of OHSS

The review found no eligible studies for this question.

1 finding from 1 review

Volume expanders for the prevention of ovarian hyperstimulation syndrome 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Thoracic epidural anaesthesia vs conventional pain control

Adverse effects of epidural anaesthesia ‐ not reported · Patients undergoing thoracotomy

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Adverse effects · Patients with non‐trauma related out‐of‐hospital cardiac arrest

1 finding from 1 review

Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation of non‐asphyxial… 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Continuous chest compression plus ventilation vs interrupted chest compression plus artificial ventilation

Adverse effects Defined as any adverse event occurring post‐admission · Patients with non‐trauma related out‐of‐hospital cardiac arrest

1 finding from 1 review

Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation of non‐asphyxial… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 23711 participants
Moderate

4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:200,000 epinephrine vs 0.5% bupivacaine, 1:200,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% prilocaine plain vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: See comment; 0 participants (0 studies); 1 case of prolonged anaesthesia recorded; no clinical studies met the outcome definition (unable to confirm whether prolonged anaesthesia = paraesthesia).
0 studies
No studies found

3% prilocaine, 0.03 IU felypressin vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

2% mepivacaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

4% articaine, 1:100,000 epinephrine vs 2% mepivacaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

0.5% bupivacaine, 1:200,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: paraesthesia following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

The review found no eligible studies for this question.

1 finding from 1 review

Injectable local anaesthetic agents for dental anaesthesia 2018 · Cochrane All outcomes
SoF: Not measured.
0 studies
No studies found

Adhesively bonded amalgam restorations in conventional preparations utilising deliberate retention (all bonding agents) vs Amalgam restoration

Adverse effects · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…

The review found no eligible studies for this question.

1 finding from 1 review

Adhesively bonded versus non‐bonded amalgam restorations for dental caries 2016 · Cochrane All outcomes
Adverse effects: any event for which the causal relationship between the event and the amalgam restoration is at least a reasonable possibility - not measured | See comment | See comment | Not estimable | - | See…
0 studies
No studies found

Regional anaesthesia vs conventional pain control

Adverse effects of paravertebral block for breast cancer surgery · women with breast cancer undergoing elective surgery

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse effects from chest radiographs · adults and children with clinical signs and symptoms of acute lower respiratory tract infection

The review found no eligible studies for this question.

1 finding from 1 review

Chest radiographs for acute lower respiratory tract infections 2013 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adverse effects of local or regional anaesthesia ‐ not reported · women after caesarean section

The review found no eligible studies for this question.

1 finding from 1 review

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain… 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topiramate vs placebo

Paraesthesia · people with drug‐resistant focal epilepsy

Topiramate probably leads to higher adverse effects ‐ paraesthesia compared with placebo (moderate certainty).

1 finding from 1 review

Topiramate add‐on therapy for drug‐resistant focal epilepsy 2019 · Cochrane Headline outcomes only
RR 3.65 [1.58, 8.39]
7 studies · 1071 participants
Moderate

Summary of findings table 3: comparison of operation types: firebreak skin grafting vs z‐plasty closure of fasciectomy

Hypoaesthesia Major outcome group 5 (adverse effects) · 79 participants (Ullah 2009)

1 finding from 1 review

Surgery for Dupuytren's contracture of the fingers 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
Low

Anaesthesia depth monitors (BIS) vs standard monitoring

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Anaesthetic interventions for prevention of awareness during surgery 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found