Findings

What do systematic reviews say?

65 questions · 66 findings · 21 reviews

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No studies found 33 · 50%GRADE not reported 9 · 13.6%Very low 17 · 25.8%Low 0 · 0%Moderate 7 · 10.6%High 0 · 0%

Double primary (canine and first molar) tooth extraction vs Single primary (canine) tooth extraction

Any other adverse effects of the interventions, such as gingival disease and demineralisation · Young people aged 9 to 14 years diagnosed with one or both palatally displaced permanent maxillary canines (PDC)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
The studies did not report adverse events.
0 studies
No studies found

Extraction of the primary (baby) canine (single primary tooth extraction) vs No extraction (non-intervention control)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for promoting the eruption of palatally displaced permanent canine teeth, without the need for surgical… 2021 · Cochrane All outcomes
Only root resorption was assessed; other adverse effects (gingival disease, demineralisation) were not reported.
0 studies
No studies found

Light vibrational forces (LVF) vs Conventional orthodontic appliance treatment

Harms: non-serious adverse effects (headache, discomfort, loosening of temporary anchorage devices) · Adolescents and adults with malocclusion undergoing orthodontic treatment with fixed or removable appliances

Light vibrational forces (LVF) showed no clear difference in harms: non-serious adverse effects (headache, discomfort, loosening… compared with conventional orthodontic appliance treatment (placebo or no adjunct); GRADE not reported.

1 finding from 1 review

Non‐surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment 2023 · Cochrane All outcomes
RR 0.96 [0.32, 2.85]
1 study · 45 participants
GRADE not reported

Mosaicplasty vs microfracture

Failure of treatment and adverse effects: long‐term Participants with surgery and symptom recurrence · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes failure of treatment and adverse effects: long‐term Participants… compared with microfracture (very low certainty).

1 finding from 1 review

Surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated… 2016 · Cochrane Headline outcomes only
RR 0.47 [0.24, 0.9]
3 studies · 129 participants
Very low

Summary of Findings Table ‐ Large retro‐equatorial recession of horizontal rectus muscle of 9 mm on the medial rectus and 12 mm on the lateral rectus vs simple tenotomy and resuturing of the 4 horizontal rectus muscles

Change in proportion of participants with adverse effects with a probable causal link to the treatment · infantile nystagmus syndrome

1 finding from 1 review

Surgical interventions for infantile nystagmus syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 10 participants
Very low