Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 0 · 0%High 1 · 50%

Angiotensin‐converting enzyme inhibitors vs ARB

Withdrawals due to adverse events · people with primary hypertension

All angiotensin converting enzyme (ACE) inhibitors leads to lower withdrawal due to adverse effects compared with all angiotensin receptor blockers (ARBs) (high certainty).

1 finding from 1 review

Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension 2014 · Cochrane Headline outcomes only
RR 0.83 [0.74, 0.93]
8 studies · 10963 participants
High

Any antihypertensive drug vs placebo or no treatment

Withdrawals due to adverse events · adults 60 years or older with primary hypertension

Antihypertensive drug may leads to higher withdrawals due to adverse effects Mean duration of 4.6 years compared with placebo or no treatment (low certainty).

1 finding from 1 review

Pharmacotherapy for hypertension in adults 60 years or older 2019 · Cochrane Headline outcomes only
RR 2.91 [2.56, 3.3]
4 studies · 11310 participants
Low