Question · asked by 1 review
Angiotensin‐converting enzyme inhibitors vs ARB: Withdrawals due to adverse events
- Population
- people with primary hypertension
- Intervention
- Angiotensin‐converting enzyme inhibitors
- Comparison
- ARB
- Outcome
- Withdrawals due to adverse events
All angiotensin converting enzyme (ACE) inhibitors leads to lower withdrawal due to adverse effects compared with all angiotensin receptor blockers (ARBs) (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
All angiotensin converting enzyme (ACE) inhibitors vs all angiotensin receptor blockers (ARBs) Withdrawal due to adverse effects · people with primary hypertension All angiotensin converting enzyme (ACE) inhibitors leads to lower withdrawal due to adverse effects compared with all angiotensin receptor blockers (ARBs) (high certainty). Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension (2014) · Cochrane Headline outcomes only | RR 0.83 [0.74, 0.93] | 8 studies · 10963 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Angiotensin converting enzyme (ACE) inhibitors versus angiotensin receptor blockers for primary hypertension 2014 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.